Elsevier

Journal of Psychosomatic Research

Review article

How does PTSD treatment affect cardiovascular, diabetes and metabolic disease take a chance factors and outcomes? A systematic review

Abstruse

Objective

Prior enquiry indicates PTSD is associated with cardiovascular and metabolic illness. A number of different treatments for PTSD tin can be effective in reducing PTSD symptoms. The aim of this study is to systematically review studies which determine whether handling for PTSD is associated with ameliorate cardiovascular and metabolic outcomes.

Method

5 different databases were searched in a systematic fashion, and 11 relevant studies were recovered and analyzed.

Findings

Treatments associated with PTSD improvement and found to be effective in improving cardiovascular or metabolic outcomes amid individuals with PTSD include cognitive behavioral therapy (heart rate variability and claret pressure), prolonged exposure (middle rate and heart rate variability) and SSRIs (blood force per unit area).

Conclusions

Multiple PTSD handling modalities were associated with improved cardiovascular health and reduced take chances of cardiovascular-related bloodshed. Given the small sample sizes, lack of follow-upwardly studies and the all-encompassing use of war machine populations in studies on PTSD and chronic diseases, these results should be interpreted with caution. More studies are needed that assess and verify whether PTSD treatments mitigate the take chances for metabolic, diabetic and cardiovascular affliction.

Introduction

Persons with posttraumatic stress disorder (PTSD) have elevated rates of metabolic disease [23,[29], [38]], metabolic syndrome [[27], [36]] and cardiovascular affliction [eight]. At that place is also evidence that PTSD increases the likelihood of type 2 diabetes (T2D), too as leads to weight gain, hypertension and hyperlipidemia. PTSD affects these metabolic and cardiovascular outcomes through a diversity of dissimilar pathways which include stress regulation and related physiological abnormalities [20,23], too equally poor wellness behaviors such every bit college substance utilise (smoking, alcohol use), more sedentary lifestyle, and poor nutrition ([31]

In comparison to the big literature on depression treatment and physical health outcomes, there is relatively piddling known almost the potential benefit of handling of posttraumatic stress disorder (PTSD) on cardiometabolic disease risk. Decades of enquiry on depression and physical health outcomes accept established PTSD as a risk factor for poor ischemic heart disease outcomes [23]. Meanwhile, there has been a number of review studies showing that adequate depression treatment is associated with reduced risk for T2D and CVD [6,16,35]). Even so, to our knowledge, in that location has not been a systematic review assessing the relationship betwixt PTSD handling and modify in co-morbid metabolic, diabetic and cardiovascular parameters. The purpose of this systematic review is to evaluate the show for an association between PTSD treatment and incident cardiometabolic diseases.

Nosotros hypothesized that receipt of handling for PTSD would be associated with decreased risk for cardiometabolic disease and comeback in components of prevalent cardiometabolic affliction. Nosotros, therefore, conducted a systematic review to explore whether treatment of PTSD was associated with a change in various measures of cardiovascular affliction and diabetes, including metabolic measures, heart charge per unit, blood pressure level, cholesterol, cardiovascular bloodshed, respiratory rate, etc.

Department snippets

Methods

We conducted a systematic literature review to identify studies which examined the effects of PTSD treatments on metabolic, cardiovascular disease and diabetes outcomes. Cardiovascular illness and diabetes health outcomes included common measures of metabolic syndrome, such as glycemic control, blood pressure, triglycerides etc., besides as incidence of and mortality due to diabetes and cardiovascular disease.

Kickoff, we identified literature from five different databases including EBSCO, PubMed,

Results

We identified 1241 citations from all sources. After removing duplicates and articles that were irrelevant (north = 1182), we reviewed the full text of 59 articles. Of these, 47 were excluded at the full text screening stage, leaving 12 articles for inclusion in the review (Fig. ane). After reviewing whether PTSD treatment affected chronic disease outcomes (i.e., metabolic, cardiovascular, diabetic), we removed the article from Scherrer et al. [19] because it did not direct measure out the relationship

Word

Results of this systematic review of PTSD treatment and risk for indicators of cardiometabolic affliction suggests that a range of unlike PTSD treatments and related reductions in PTSD severity are associated with improved cardiometabolic disease severity or lower cardiometabolic illness gamble. However, some of the interventions, like ECT and devise guided animate, were not traditionally used to treat PTSD and in that location were no follow-up studies which confirmed results of these studies. Nosotros plant

Conclusions

PTSD is a well-established risk gene for numerous health problems. Our results betoken several types of PTSD treatments and symptom improvement can reduce some take chances factors associated with cardiometabolic disease, such as blood pressure. Educating patients about the secondary health benefits of PTSD treatment may encourage more treatment seeking. Additional research is needed to identify the mechanisms underlying the link between PTSD handling, reduced PTSD severity and cardiometabolic

Funding

This projection is supported by the National Center, Lung, and Blood Found, PTSD Treatment: Effects on Health Behavior, Cardiovascular and Metabolic Disease, R01HL125424 and the Wellness Resources and Services Administration (HRSA) of the U.S. Department of Health and Man Services (HHS) under grant number U77HP03042 entitled "MAHEC 2017-2022: A Statewide Network for Interprofessional Health Care Workforce Evolution and Practice Transformation in Rural and Underserved Missouri" for $1,903,160

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